Contrary to popular belief, a new study has shown that rolling isn’t that bad for you. The study was published in the Journal of Psychopharmacology. The study suggests that previous research overestimated the extent of serotonergic alterations experienced by the majority of users. MDMA, the primary component of ecstasy, releases serotonin which creates the feel-good high while rolling. However, MDMA gives users a rough emotional crash from depleted serotonin levels after use.
MDMA alters the brain’s serotonergic levels in a dose-dependent manner. However, the relevance of these findings remains unclear due to limited knowledge about the ecstasy/MDMA use pattern of real-life users.
Balázs Szigeti, a researcher at the University of Edinburgh, looked at previous reports and had an issue with its findings. “I found it weird that they called users who take 2 pills twice a month ‘low to moderate users.’ I suspected that it is much more than what the average user takes,” Szigeti said. He realized that The Global Drug Survey was likely to have the data he needed. He quickly emailed them:
In conclusion, the study findings suggest that the brain imaging was focused mainly on unusually heavy ecstasy use. Therefore, the conclusions likely overestimate the extent of serotonin level alterations. The whole study can be found here.